Table 2.
uEPSP properties of L6 upright- and inverted-preconnections under control and adenosine conditions
| Ctrl | Adenosine 30 µM | Wilcoxon signed-rank test | Ctrl | Adenosine 10 µM | Wilcoxon signed-rank test | |
|---|---|---|---|---|---|---|
| Upright-pre connections (n = 8 connections from 8 rats) | ||||||
| 1st EPSP amplitude (mV) | 0.25 ± 0.23 | 0.05 ± 0.04 | *0.0313 | 0.24 ± 0.27 | 0.04 ± 0.04 | *0.0156 |
| Normalized 1st EPSP amplitude (%) | - | 27 ± 16 | - | - | 19 ± 4 | - |
| Paired-pulse ratio | 1.67 ± 1.04 | 4.05 ± 3.65 | *0.0313 | 1.20 ± 0.62 | 2.41 ± 2.58 | 0.1094 |
| Coefficient of variation | 1.14 ± 0.61 | 1.34 ± 0.39 | 0.3125 | 1.06 ± 0.30 | 1.25 ± 0.37 | 0.5781 |
| Failure rate (%) | 58.7 ± 33.3 | 80.6 ± 16.2 | *0.0313 | 59.1 ± 17.0 | 83.4 ± 4.0 | *0.0313 |
| Rise time (ms) | 0.91 ± 0.22 | 1.25 ± 0.30 | 0.2188 | 1.13 ± 0.28 | 0.71 ± 0.19 | 0.7656 |
| Latency (ms) | 1.55 ± 0.63 | 1.56 ± 0.80 | 0.5781 | 1.46 ± 0.60 | 1.31 ± 0.70 | 0.5625 |
| Decay time (ms) | 28.5 ± 29.8 | 27.4 ± 27.1 | 0.8438 | 22.2 ± 14.5 | 23.7 ± 19.3 | 0.5781 |
| Inverted-pre connections (n = 8 connections from 8 rats) | ||||||
| 1st EPSP amplitude (mV) | 0.99 ± 0.62 | 0.17 ± 0.15 | **0.0078 | 1.20 ± 0.89 | 0.68 ± 0.52 | *0.0156 |
| Normalized 1st EPSP amplitude (%) | - | 25 ± 21 | - | - | 58 ± 19 | - |
| Paired-pulse ratio | 0.67 ± 0.13 | 1.54 ± 0.93 | *0.0156 | 0.89 ± 0.32 | 0.89 ± 0.23 | 0.8906 |
| Coefficient of variation | 0.60 ± 0.16 | 1.21 ± 0.29 | **0.0078 | 0.70 ± 0.27 | 0.89 ± 0.26 | 0.0781 |
| Failure rate (%) | 13.6 ± 12.2 | 68.9 ± 13.9 | **0.0039 | 25.2 ± 21.8 | 38.1 ± 20.7 | *0.0469 |
| Rise time (ms) | 1.44 ± 0.74 | 1.31 ± 0.87 | 0.5469 | 1.56 ± 0.73 | 1.32 ± 0.79 | 0.1719 |
| Latency (ms) | 1.32 ± 0.47 | 1.24 ± 0.67 | 0.6406 | 1.38 ± 0.45 | 1.89 ± 1.02 | 0.1563 |
| Decay time (ms) | 46.6 ± 25.8 | 46.1 ± 42.8 | 0.5273 | 40.5 ± 15.7 | 35.9 ± 38.0 | 0.6875 |
-
Bold italic font indicates significant differences to control; *p < 0.05, **p < 0.01 for Wilcoxon signed-rank test.
