Table 2.
Drugs used in whole brains from juvenile zebrafish
| Drug name | Final bath concentration | Function | Company | Catalog # |
|---|---|---|---|---|
| (2R)-2-Amino-5-phosphonopentanoic acid (AP-5) | 30 µM | Blocks N-methyl-D-aspartate (NMDA) |
Sigma-Aldrich – Sigma-Aldrich |
165304 |
| 2,3-Dioxo-6-nitro-7-sulfamoyl-benzo[f]quinoxaline (NBQX) | 5 µM | Blocks α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) | N183 | |
| AP-5 + NBQX | 25 µM AP-5 + 5 µM NBQX | Blocks ionotropic glutamate transmission | – | |
| Bicuculline methiodide (BMI) | 30 µM | Blocks GABAA receptors | 14343 | |
| 6-cyano-7nitroquinoxaline-2,3-dione (CNQX) | 10 µM | Competitive AMPA/Kainate receptor antagonist | Sigma-Aldrich | C127 |
| Atropine | 10 µM | Blocks muscarinic receptors | Sigma-Aldrich | 1044990 |
| Mecamylamine hydrochloride (MEC) | 20 µM | Noncompetitive nicotinic receptor antagonist | Sigma-Aldrich | 1376006 |
