This Week in The Journal
Disentangling Ventral Frontal Cortex Subregion Roles in Behavior
Frederic Stoll and Peter Rudebeck
(see article e0464242024)
The ventral frontal cortex (VFC) plays key roles in flexible reward-based decision-making. But the VFC has anatomically distinct subregions and their contributions to flexibly making reward-based decisions is unclear. Furthermore, whether their roles are dissociable is unexplored. Stoll and Rudebeck explored these unknowns in male macaque monkeys. They recorded from neurons in eight anatomically defined VFC subregions as macaques chose between cues associated with distinct reward probabilities and …
