mEPSC properties and recording conditions in NR, 2 d MD, 6 d MD + vehicle, and 6 d MD + Ro 25-6981 groups (related to Fig. 1)
| Amplitude (pA) | Frequency (Hz) | Rise (ms) | Decay (ms) | Rin (MW) | Rs (MW) | RMS | N | ||
|---|---|---|---|---|---|---|---|---|---|
| NR | Ipsi | 13.3 ± 0.4 | 7.87 ± 0.6 | 0.76 ± 0.02 | 2.56 ± 0.1 | 273 ± 13 | 16.8 ± 0.3 | 1.84 ± 0.02 | 27, 5 |
| Contra | 13.3 ± 0.4 | 8.90 ± 0.6 | 0.75 ± 0.02 | 2.56 ± 0.1 | 294 ± 12 | 16.2 ± 0.3 | 1.82 ± 0.02 | 29, 5 | |
| Statistic | t(54) = 0.06 | t(54) = 1.2 | U = 390.5 | t(54) = 0.03 | U = 289 | t(54) = 1.2 | U = 358.5 | ||
| p | 0.95 | 0.22 | 0.99 | 0.97 | 0.09 | 0.2 | 0.59 | ||
| 2 d MD | Ipsi | 13.5 ± 0.4 | 7.71 ± 0.5 | 0.80 ± 0.03 | 2.79 ± 0.1 | 305 ± 19 | 16.4 ± 0.4 | 1.81 ± 0.02 | 30, 6 |
| Contra | 11.9 ± 0.3 | 9.06 ± 0.6 | 0.83 ± 0.03 | 2.85 ± 0.1 | 297 ± 18 | 16.5 ± 0.4 | 1.79 ± 0.02 | 32, 6 | |
| statistic | t(60) = 2.9 | t(60) = 1.7 | U = 467 | U = 458.5 | U = 451 | t(60) = 0.35 | t(60) = 0.66 | ||
| p | 0.005* | 0.10 | 0.86 | 0.77 | 0.69 | 0.73 | 0.51 | ||
| 6 d MD vehicle | Ipsi | 12.3 ± 0.4 | 6.69 ± 0.5 | 0.81 ± 0.02 | 2.67 ± 0.1 | 307 ± 33 | 16.0 ± 0.4 | 1.81 ± 0.02 | 23, 5 |
| Contra | 13.4 ± 0.3 | 6.98 ± 0.5 | 0.78 ± 0.02 | 2.70 ± 0.1 | 271 ± 14 | 16.6 ± 0.3 | 1.81 ± 0.02 | 28, 5 | |
| statistic | t(49) = 2.6 | U = 308 | t(49) = 0.81 | U = 305 | U = 258.5 | t(49) = 1.2 | t(49) = 0.007 | ||
| p | 0.012* | 0.80 | 0.42 | 0.75 | 0.23 | 0.26 | 0.99 | ||
| 6 d MD Ro 25-6981 | Ipsi | 13.8 ± 0.3 | 7.40 ± 0.5 | 0.82 ± 0.03 | 2.77 ± 0.1 | 282 ± 13 | 16.1 ± 0.4 | 1.80 ± 0.02 | 24, 5 |
| Contra | 12.4 ± 0.4 | 7.49 ± 0.6 | 0.85 ± 0.02 | 2.89 ± 0.1 | 318 ± 19 | 16.9 ± 0.5 | 1.81 ± 0.02 | 27, 5 | |
| Statistic | t(49) = 2.8 | t(49) = 0.11 | t(49) = 0.92 | t(49) = 1.09 | U = 249.5 | t(49) = 1.1 | t(49) = 0.30 | ||
| p | 0.0075* | 0.91 | 0.36 | 0.28 | 0.16 | 0.3 | 0.77 |
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For each treatment, data were compared between control (ipsi) and deprived (contra) hemispheres using two-tailed unpaired t tests (t statistic reported) or Mann–Whitney tests (U statistic reported), as indicated. Bold values indicate significant differences. Data are shown as mean ± SEM. N is reported as cells, mice.
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*p < 0.005.




