Table 2.
Arterial blood gas analysis of GPR4(HF) mutant mouse lines
| Genotype | WT (12) | H81F (13) | Jx99 (13) | H81F-Jx (13) | WT (15) | H167F (14) |
|---|---|---|---|---|---|---|
| pH | 7.40 ± 0.01 | 7.44 ± 0.02* | 7.44 ± 0.01 | 7.44 ± 0.02 | 7.42 ± 0.01 | 7.42 ± 0.02 |
| PCO2 (mmHg) | 30.4 ± 1.2 | 34.3 ± 1.5 | 30.8 ± 0.9 | 29.9 ± 2.2 | 33.5 ± 1.0 | 31.2 ± 1.0 |
<mml:math display="inline"><mml:mrow><mml:mi mathvariant="normal">HC</mml:mi></mml:mrow><mml:msubsup><mml:mrow><mml:mi mathvariant="normal">O</mml:mi></mml:mrow><mml:mn>3</mml:mn><mml:mo>−</mml:mo></mml:msubsup></mml:math>HCO3− (mM)
|
19.8 ± 0.9 | 24.3 ± 0.9** | 21.2 ± 0.9 | 20.3 ± 1.5 | 21.7 ± 0.8 | 20.2 ± 0.9 |
| PO2 (mmHg) | 84.3 ± 3.3 | 89.9 ± 2.3 | 87.0 ± 2.5 | 89.9 ± 4.1 | 85.8 ± 2.2 | 91.2 ± 2.3 |
| lactate (mM) | 3.7 ± 0.7 | 3.4 ± 0.3 | 2.7 ± 0.4 | 3.7 ± 0.4 | 4.0 ± 0.5 | 4.0 ± 0.5 |
