ELP1, the Gene Mutated in Familial Dysautonomia, Is Required for Normal Enteric Nervous System Development and Maintenance and for Gut Epithelium Homeostasis

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Figure 4.
Figure 4.

Glial cells and ICCs are reduced in number in the adult Tuba1a-Cre;Elp1loxp/loxp proximal duodenum. A, B, Sections were immunolabeled with antibodies to S100b to visualize glia (green) and to CD117 to visualize ICC (red), and the signal intensity of the area of expression quantified (B); multiple unpaired t tests; *p = 0.025, **p = 0.0047, n = 6.

  1. The Journal of Neuroscience vol. 44 no. 37
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