Apoptosis is increased in the adult Tuba1a-Cre;Elp1^loxp/loxp Elp1 cKO ileum myenteric plexus. A, B, Ileum whole mounts were immunolabeled with antibodies to neurons (Hu, green) and to cleaved Caspase-3 (red) and the number of cleaved caspase-3-positive neurons determined in 10 fields per mouse in three mice each. B, Quantification shows a significant increase in cleaved caspase-3-positive neurons in the cKO (unpaired t test p = 0.0239). See Extended Data Figure 8.1 for more details.