An example of the effects of ketamine on the aperiodic and oscillatory components of the LFPs. A, Ketamine reduced both the exponent (visible as the slope) and the offset of the aperiodic component of the LFP power (visible as the lower position of intersection with the y-axis; dashed, pre-injection; solid, post-injection). B, In this case, ketamine increased the central frequency of the oscillatory component of the LFP, without changing its amplitude. C, Total LFP power with both the aperiodic and oscillatory components combined.