Age-related changes in the timescale of rs-fMRI signals. a, Brain maps of the age coefficient for timescale in Child (left), Adult (middle), and Old (right) age groups. Gray regions indicate the ROI in which the age effect was not statistically significant (p > 0.05). b, Scatter plots of the average timescale (lag-1 TA) for the entire cortex across individual subjects. The red line represents the LOWESS fit and vertical dotted lines show the border between age groups. c, LOWESS fit for timescale in each FC network. Dotted/dashed lines show networks that are significantly more positive/negative than the average (see also Table 2). The values for the Adult age group were increased by 0.087 to compensate for the discontinuations at the age boundaries shown in b. d, Peak ages for timescales in networks with significant non-monotonic time course in the Child age group. The black vertical line and gray bar correspond to the mean ± SD.