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Research Articles - Neurobiology of Disease
:
Synchronized Photoactivation of T4K Rhodopsin Causes a Chromophore-Dependent Retinal Degeneration That Is Moderated by Interaction with Phototransduction Cascade Components
Beatrice M. Tam
,
Paloma Burns
,
Colette N. Chiu
,
and
Orson L. Moritz
The Journal of Neuroscience
,
4 September 2024,
44
(
36
):
e0453242024
;
published ahead of print
August 1, 2024
,
doi:
10.1523/JNEUROSCI.0453-24.2024
Abstract
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Research Articles - Neurobiology of Disease
:
Opposing Effects of Valproic Acid Treatment Mediated by Histone Deacetylase Inhibitor Activity in Four Transgenic
X. laevis
Models of Retinitis Pigmentosa
Ruanne Y.J. Vent-Schmidt
,
Runxia H. Wen
,
Zusheng Zong
,
Colette N. Chiu
,
Beatrice M. Tam
,
Christopher G. May
,
and
Orson L. Moritz
The Journal of Neuroscience
,
25 January 2017,
37
(
4
):
1039
-
1054
;
published ahead of print
December 9, 2016
,
doi:
10.1523/JNEUROSCI.1647-16.2016
Abstract
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Articles - Neurobiology of Disease
:
Photoactivation-Induced Instability of Rhodopsin Mutants T4K and T17M in Rod Outer Segments Underlies Retinal Degeneration in
X. laevis
Transgenic Models of Retinitis Pigmentosa
Beatrice M. Tam
,
Syed M. Noorwez
,
Shalesh Kaushal
,
Masahiro Kono
,
and
Orson L. Moritz
The Journal of Neuroscience
,
1 October 2014,
34
(
40
):
13336
-
13348
;
doi:
10.1523/JNEUROSCI.1655-14.2014
Abstract
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Articles - Cellular/Molecular
:
Dysmorphic Photoreceptors in a P23H Mutant Rhodopsin Model of Retinitis Pigmentosa Are Metabolically Active and Capable of Regenerating to Reverse Retinal Degeneration
Damian C. Lee
,
Felix R. Vazquez-Chona
,
W. Drew Ferrell
,
Beatrice M. Tam
,
Bryan W. Jones
,
Robert E. Marc
,
and
Orson L. Moritz
The Journal of Neuroscience
,
8 February 2012,
32
(
6
):
2121
-
2128
;
doi:
10.1523/JNEUROSCI.4752-11.2012
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Articles - Neurobiology of Disease
:
Dark Rearing Rescues P23H Rhodopsin-Induced Retinal Degeneration in a Transgenic
Xenopus laevis
Model of Retinitis Pigmentosa: A Chromophore-Dependent Mechanism Characterized by Production of N-Terminally Truncated Mutant Rhodopsin
Beatrice M. Tam
and
Orson L. Moritz
The Journal of Neuroscience
,
22 August 2007,
27
(
34
):
9043
-
9053
;
doi:
10.1523/JNEUROSCI.2245-07.2007
Abstract
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Cellular/Molecular
:
Mislocalized Rhodopsin Does Not Require Activation to Cause Retinal Degeneration and Neurite Outgrowth in
Xenopus laevis
Beatrice M. Tam
,
Guifu Xie
,
Daniel D. Oprian
,
and
Orson L. Moritz
The Journal of Neuroscience
,
4 January 2006,
26
(
1
):
203
-
209
;
doi:
10.1523/JNEUROSCI.3849-05.2006
Abstract
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