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Research Articles - Neurobiology of Disease
:
Human Brain-Derived Aβ Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP
Zemin Wang
,
Rosemary J. Jackson
,
Wei Hong
,
Walter M. Taylor
,
Grant T. Corbett
,
Arturo Moreno
,
Wen Liu
,
Shaomin Li
,
Matthew P. Frosch
,
Inna Slutsky
,
Tracy L. Young-Pearse
,
Tara L. Spires-Jones
,
and
Dominic M. Walsh
The Journal of Neuroscience
,
6 December 2017,
37
(
49
):
11947
-
11966
;
published ahead of print
November 3, 2017
,
doi:
10.1523/JNEUROSCI.2009-17.2017
Abstract
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Articles - Neurobiology of Disease
:
Reversal of Neurofibrillary Tangles and Tau-Associated Phenotype in the rTgTauEC Model of Early Alzheimer's Disease
Manuela Polydoro
,
Alix de Calignon
,
Marc Suárez-Calvet
,
Laura Sanchez
,
Kevin R. Kay
,
Samantha B. Nicholls
,
Allyson D. Roe
,
Rose Pitstick
,
George A. Carlson
,
Teresa Gómez-Isla
,
Tara L. Spires-Jones
,
and
Bradley T. Hyman
The Journal of Neuroscience
,
14 August 2013,
33
(
33
):
13300
-
13311
;
doi:
10.1523/JNEUROSCI.0881-13.2013
Abstract
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Articles - Neurobiology of Disease
:
Apolipoprotein E, Especially Apolipoprotein E4, Increases the Oligomerization of Amyloid β Peptide
Tadafumi Hashimoto
,
Alberto Serrano-Pozo
,
Yukiko Hori
,
Kenneth W. Adams
,
Shuko Takeda
,
Adrian Olaf Banerji
,
Akinori Mitani
,
Daniel Joyner
,
Diana H. Thyssen
,
Brian J. Bacskai
,
Matthew P. Frosch
,
Tara L. Spires-Jones
,
Mary Beth Finn
,
David M. Holtzman
,
and
Bradley T. Hyman
The Journal of Neuroscience
,
24 October 2012,
32
(
43
):
15181
-
15192
;
doi:
10.1523/JNEUROSCI.1542-12.2012
Abstract
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Articles - Neurobiology of Disease
:
Inhibition of the NFAT Pathway Alleviates Amyloid Beta Neurotoxicity in a Mouse Model of Alzheimer's Disease
Eloise Hudry
,
Hai-Yan Wu
,
Michal Arbel-Ornath
,
Tadafumi Hashimoto
,
Roland Matsouaka
,
Zhanyun Fan
,
Tara L. Spires-Jones
,
Rebecca A. Betensky
,
Brian J. Bacskai
,
and
Bradley T. Hyman
The Journal of Neuroscience
,
29 February 2012,
32
(
9
):
3176
-
3192
;
doi:
10.1523/JNEUROSCI.6439-11.2012
Abstract
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Articles - Neurobiology of Disease
:
Amyloid β Induces the Morphological Neurodegenerative Triad of Spine Loss, Dendritic Simplification, and Neuritic Dystrophies through Calcineurin Activation
Hai-Yan Wu
,
Eloise Hudry
,
Tadafumi Hashimoto
,
Kishore Kuchibhotla
,
Anete Rozkalne
,
Zhanyun Fan
,
Tara Spires-Jones
,
Hong Xie
,
Michal Arbel-Ornath
,
Cynthia L. Grosskreutz
,
Brian J. Bacskai
,
and
Bradley T. Hyman
The Journal of Neuroscience
,
17 February 2010,
30
(
7
):
2636
-
2649
;
doi:
10.1523/JNEUROSCI.4456-09.2010
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Brief Communications
:
In Vivo
Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons
Tara L. Spires-Jones
,
Alix de Calignon
,
Toshifumi Matsui
,
Cindy Zehr
,
Rose Pitstick
,
Hai-Yan Wu
,
Jennifer D. Osetek
,
Phillip B. Jones
,
Brian J. Bacskai
,
Mel B. Feany
,
George A. Carlson
,
Karen H. Ashe
,
Jada Lewis
,
and
Bradley T. Hyman
The Journal of Neuroscience
,
23 January 2008,
28
(
4
):
862
-
867
;
doi:
10.1523/JNEUROSCI.3072-08.2008
Abstract
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