Corticotropin-Releasing Factor and Somatostatin Neurons in the Central Amygdala Mediate Dynamic Defensive Behaviors during Fear Extinction

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 7.
Figure 7.

SOM+ CEA neuron manipulation during extinction has little effect on post-extinction freezing and speed. A, Comparison of average freezing during the tone period in the neutral context of Recall1 for all SOM-Cre groups. B, Comparison of average freezing during the tone period in the threat context of Recall2 for all SOM-Cre groups. C, Comparison of average freezing during the WN period in the neutral context of Recall1 for all SOM-Cre groups. D, Comparison of average freezing during the WN period in the threat context of Recall2 for all SOM-Cre groups. E, Comparison of average speed during the tone period in the neutral context of Recall1 for all SOM-Cre groups. F, Comparison of average speed during the WN period in the neutral context of Recall2 for all SOM-Cre groups. ChR2: n = 9, Control: n = 10, eNpHR3: n = 9. Data from all figures are presented as mean ± SEM and were analyzed with one-way ANOVA and Tukey's multiple-comparisons test. *p < 0.05.

  1. The Journal of Neuroscience vol. 46 no. 14
Responses to This Article
Be the first to respond to this article
Advertisement